Key features and details | |
Cat. No. | MABL-322 |
Name | Anti-5T4 mAbs |
Clone No. | AFD- 12B12C7C3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | functional assay, ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for TPBG. It does not bind to the same epitope as 39A11G5F2. |
Alternative Name | TPBG; M6P1; WAIF1; Trophoblast glycoprotein; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; Wnt-activated inhibitory factor 1 |
UniProt | Q13641 |
Immunogen | The original antibody was generated by immunizing BALB/cAnNCrl mice or SJL/JorllcoCrl mice with either full length TPBG or amino acid sequence 32-355 from TPBG. |
Application Notes | An ELISA was performed on this antibody with TPBG protein (EP3395834). This antibody was used for flow cytometry on a CHOK1 cell line transformed to contain full-length human TPBG (EP3395834). A cytotoxicity assay was performed on TPBG-negative tumor cell line NCI-H1770 using this antibody conjugated with MMF (EP3395834). |
Antibody First Published | Xiaolan et al. Tpbg antibody and preparation method therefor, conjugate and use thereof. EP3395834A4 PMID: |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |