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Anti-Transferrin mAbs

简要描述:

Binds to the N-terminal domain of human transferrin.

产品参数:

Cat. No.:MABL-3130

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:WB, Block, ELISA, FC

详细介绍

Key features and   details


Cat. No.

MABL-3130

Name

Anti-Transferrin mAbs

Clone No.

AFD- TW4.20

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, Block, ELISA, FC

Species Reactivity

Human

Basic Information


Specificity

Binds to the N-terminal domain of human   transferrin.

Alternative Name

Serotransferrin

UniProt

Q06AH7

Immunogen

Iron-free purified human transferrin.

Application Notes

This antibody recognises transferrin a   protein which can bind two Fe3+ ions in association with the binding of an   anion, usually bicarbonate. It is responsible for the transport of iron from   sites of absorption and heme degradation to those of storage and utilization.   Serum transferrin may also have a further role in stimulating cell   proliferation. This antibody can displace transferrin from the transferrin   receptor.

Antibody First   Published

Orlandini et al. Cloning, characterization,   and modeling of a monoclonal anti- human transferrin antibody that competes   with the transferrin receptor Protein Sci. 3 (9), 1476-1484 (1994)   PMID:7530542

Note on publication

Describes the generation and characterisation of this antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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