Key features and details | |
Cat. No. | MABL-3112 |
Name | Anti-TLR4 mAbs |
Clone No. | AFD- 52-1H4 e2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | antagonist, ELISA |
Species Reactivity | Rat |
Basic Information | |
Specificity | This antibody binds rat toll like receptor 4. |
Alternative Name | CD284; Tlr4; Toll-like receptor 4; Toll4; TLR4/MD2 |
UniProt | Q9QX05 |
Immunogen | |
Application Notes | This antibody was reported to completely inhibit lipopolysaccharide-induced interleukin-6 secretion in vitro. The binding of this antibody to rat cells stable expressing TLR4/MD2 was done using ELISA (PMID: 33290148). |
Antibody First Published | Sato et al. Generation and characterization of a novel anti-rat TLR4/MD2 antibody with potent neutralizing activity in vivo. Monoclon Antib Immunodiagn Immunother. 2020 Dec;39(6):217-221. PMID:33290148 |
Note on publication | Describes the generation and characterization of rat TLR4/MD2 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
