Key features and details | |
Cat. No. | MABL-3103 |
Name | Anti-TLR3 mAbs |
Clone No. | AFD-11F8.1B7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IHC, FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | The original antibody is specific for mouse Toll-like receptor 3 (TLR3) extracellular domain. |
Alternative Name | CD283; TLR3 extracellular domain |
UniProt | Q99MB1 |
Immunogen | The original antibody was generated by immunizing rats against murine TLR3 extracellular domain. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. This antibody was used for the detection of TLR3 by immunohistochemistry (McCartney et al., 2011; PMID: 21403398). This antibody was used for detection of TLR3 expressed on RAW274.7 cells by flow cytometry (Njoroge et al., 2018; PMID: 30587965). |
Antibody First Published | McCartney et al. Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)‐mediated activation of mouse NK cells J Exp Med . 2009 Dec 21;206(13):2967-76. PMID:19995959 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
