Key features and details | |
Cat. No. | MABL-2891 |
Name | Anti-SETD7 mAbs |
Clone No. | AFD- RAB-C220 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | CHIP, IP-MS, spiked IP, ELISA, FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognizes SETD7 (Histone-lysine N-methyltransferase SETD7). It binds to a folded domain, amino acids 2-366. SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin. |
Alternative Name | SET7/9; Histone-lysine N-methyltransferase SETD7; Histone H3-K4 methyltransferase SETD7; H3-K4-HMTase SETD7; Lysine N-methyltransferase 7; SET domain-containing protein 7; anti-SETD7-RAB-C220; 48H1_2 |
UniProt | Q8WTS6 |
Immunogen | This antibody was obtained by recombinant antibody (rAb) phage display recognizing SETD7 protein under non-denaturing conditions. |
Application Notes | This antibody has been used and recommended for the following methods: ELISA; IF; spiked IP; IP-MS; ChIP; FC. |
Antibody First Published | |
Note on publication | More information on this antibody can be found on the website of the Recombinant Antibody Network. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
