Key features and details | |
Cat. No. | MABL-2826 |
Name | Anti-Rhesus IgA alpha chain mAbs |
Clone No. | AFD- 10F12 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | rhesus macaque |
Basic Information | |
Specificity | This antibody reacts with macaque IgA alpha chain. It does not react with human IgA. |
Alternative Name | α-rhesus IgA |
UniProt | |
Immunogen | |
Application Notes | A biotinylated version of this antibody has been used in ELISA analysis to quantify HIV- 1 or SIV Env-specific and total IgA in rhesus macaque plasma, milk and mucosal samples following viral infection or passive immunisation (Amos et al, 2015; Fouda et al, 2017; Eudailey et al, 2018). |
Antibody First Published | Fouda et al. Systemic administration of an HIV 1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization Mucosal Immunol. 2017 Jan; 10(1): 228–237. PMID:27072605 |
Note on publication | This antibody is from the laboratory of Keith Reimann, DVM, Beth Israel Deaconess Medical Center. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |