Key features and details | |
Cat. No. | MABL-2747 |
Name | Anti-proBNP mAbs |
Clone No. | AFD-106.3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds B-type natriuretic peptide (BNP) 5‐13 (VQGSGAFGR). BNP is a naturally secreted cardiac regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP concentration is a clinically recognized biomarker for various cardiovascular diseases. |
Alternative Name | BNP; hBNP; NPPB; preproBNP; B-type natriuretic peptide; Natriuretic peptides B; Brain natriuretic factor prohormone; Brain natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; HB-12044 |
UniProt | P16860 |
Immunogen | The original mouse antibody was generated by immunizing mice with human BNP peptide 5- 13 (VQGSGAFGR) conjugated with BSA. |
Application Notes | This antibody can be used for the detection of human BNP using ELISA (PMID: 18606632). This antibody when crosslinked to POROS XL ID resin can also be used in the immunoprecipitation of BNP from plasma samples of patients with chronic heart failure (PMID: 16750161). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
