Key features and details | |
Cat. No. | MABL-2684 |
Name | Anti-Phosphatidylglucoside mAbs |
Clone No. | AFD- rGL-7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, ELISA, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds specifically to PhGlc. |
Alternative Name | PhGlc |
UniProt | |
Immunogen | Human Peripheral Lymphocates (HPL). |
Application Notes | This antibody binds to phosphatidylglucoside, a glyco-glycerophospholipid which is involved in the signalling leading to granulocyte differentiation. The antibody stimulates rapid tyrosine phosphorylation of the Src-family protein kinases Lyn and Hck. |
Antibody First Published | Natasuka et al. Carbohydrate-dependent signaling from the phosphatidylglocisde-based microdomain induces granulocytic differentiation of HL60 cells. Proceedings of the National Academy of Sciences 2003; 100(13):7454-7459 PMID:12802014 |
Note on publication | Describes the identification of a glycolipid component in granulocytic signalling leading to CD38 expression. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
