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Anti-Phosphatidylglucoside mAbs

简要描述:

This antibody binds specifically to PhGlc.

产品参数:

Cat. No.:MABL-2684

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:IP, ELISA, IF

详细介绍

Key features and   details


Cat. No.

MABL-2684

Name

Anti-Phosphatidylglucoside   mAbs

Clone No.

AFD- rGL-7

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, ELISA, IF

Species Reactivity

Human

Basic Information


Specificity

This antibody binds specifically to PhGlc.

Alternative Name

PhGlc

UniProt


Immunogen

Human Peripheral Lymphocates (HPL).

Application Notes

This antibody binds to phosphatidylglucoside,   a glyco-glycerophospholipid which is involved in the signalling leading to  granulocyte differentiation. The antibody stimulates rapid tyrosine   phosphorylation of the Src-family protein kinases Lyn and Hck.

Antibody First   Published

Natasuka et al. Carbohydrate-dependent   signaling from the phosphatidylglocisde-based microdomain induces   granulocytic differentiation of HL60 cells. Proceedings of the National   Academy of Sciences 2003; 100(13):7454-7459 PMID:12802014

Note on publication

Describes the identification of a glycolipid   component in granulocytic signalling leading to CD38 expression.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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