Anti-PD-1 mAbs

Cat. No.

MABL-2641

Name

Anti-PD-1 mAbs

Clone No.

AFD- PD1-28

From

Recombinant Antibody

Isotype

Engineer antibody

Application

functional assay, Block, ELISA

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for PD-1.

Alternative Name

CD279; Programmed cell death protein 1;   PDCD1; PD-1; hPD-1

UniProt

Q15116

Immunogen

The original antibody was generated by panning against an scFv phagemid library generated from non-immunized human donors.

Application Notes

An ELISA was performed on PD-1 fusion protein   using this antibody (US7488802). This antibody was capable of blocking the   PD-1/PD-L1 interaction. It was found that PD1-28 can mimic PD-1 ligands and   deliver an inhibitory signal causing a decrease in T cell proliferation and   IL-2 production (US7488802).

Antibody First   Published

Collins et al. Antibodies against PD-1.   US7488802

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.