Key features and details | |
Cat. No. | MABL-2602 |
Name | Anti-panfilovirus glycoprotein mAbs |
Clone No. | AFD- 4B3B5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | panfilovirus |
Basic Information | |
Specificity | The antibody is specific for glycoproteins (GP). In particular, it targets the epitope GAFFLYDRLAST (a.k.a peptide 1), that is conserved across all ebolavirus and marburgvirus spp glycoproteins (GP) |
Alternative Name | GP1,2; GP; filovirus; filovirus Gp; Envelope glycoprotein; Virion spike glycoprotein |
UniProt | Q66810; P35253 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with the conserved B cell epitope of filovirus Gp. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis (Bongcam-Rudloff et al. 2023). |
Antibody First Published | Bongcam-Rudloff et al. Consensus DNA and amino acids sequences of the recombinant panfilovirus glycoprotein specific mAb 4B3B5 and its expression in CHO mammalian cell lines Preprint from Research Square, 01 Feb 2023. DOI: PPR610922 10.21203/rs.3.rs-2532962/v1 PPR: |
Note on publication | The paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
