Key features and details | |
Cat. No. | MABL-2590 |
Name | Anti-paclitaxel mAbs |
Clone No. | AFD- 1C2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | |
Basic Information | |
Specificity | This antibody is specific for paclitaxel, an anti-neoplastic agent derived from the Pacific yew. |
Alternative Name | PT; PTX; Taxol; 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7-xylosyltaxol |
UniProt | |
Immunogen | This antibody was raised by immunising BALB/c mice with a solution of 7-xylosyltaxol conjugated to the carrier protein bovine serum albumin (XylTax–BSA).7-xylosyltaxol is a taxol (paclitaxel) derivative, which binds to tubulin and inhibits microtubule dis |
Application Notes | The reactivity of this antibody for free and immobilised paclitaxel has been confirmed in ELISA analysis (Yusakul et al, 2018). |
Antibody First Published | Yusakul et al. Different expression systems resulted in varied binding properties of anti‑paclitaxel single‑chain variable fragment antibody clone 1C2 J Nat Med (2018) 72:310–316 PMID:29027080 |
Note on publication | Describes the original generation of this antibody, and the derivation of an scFv with the same binding specificity. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
