Key features and details | |
Cat. No. | MABL-2214 |
Name | Anti-LAG-3 mAbs |
Clone No. | AFD- 209B1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, SPR |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for human LAG-3. |
Alternative Name | CD223; LAG3; FDC; Lymphocyte activation gene 3 protein |
UniProt | P18627 |
Immunogen | The original antibody was generated by immunizing female BALB/c mice with Flag-his-tagged extracellular domain of LAG-3. |
Application Notes | The antibody is a humanized version of the mouse antibody MAB209B1. The binding affinity of the antibody to hLAG-3 was measured by surface plasmon resonance. The binding affinity of this antibody towards human LAG-3 was found to be Kd= 7.7pM. The antibody showed a good tumour inhibitory effect in in vivo application (WO2021136392). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
