Key features and details | |
Cat. No. | MABL-2037 |
Name | Anti-IL-17A mAbs |
Clone No. | AFD- 3D11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA |
Species Reactivity | Chicken |
Basic Information | |
Specificity | The antibody binds specifically to chicken IL-17, a proinflammatory cytokine produced by activated T cells. The antibody binds moderately to duck IL17. |
Alternative Name | Interleukin 17A; chIL-17; Interleukin-17A; IL-17; chicken IL-17A |
UniProt | B4ER12 |
Immunogen | The original antibody was raised by immunizing BALB/C mice with recombinant chicken IL-17. |
Application Notes | The specificity of this antibody was confirmed in ELISA analysis. The antibody detected the recombinant chIL-17A by western blot on CU205 cells. The antibody was used with Con A-stimulated splenocytes in Northern blot analysis (Yoo et al, 2008; pmid: 18022248). The cross-reactivity of the antibody to chIL17 with duck IL17 was evaluated by indirect ELISA. The antibody bound moderately to duIL17 (Yoo et al., 2009; pmid: 19573930). |
Antibody First Published | Yoo et al. Monoclonal antibodies reactive with chicken interleukin‐17. Vet Immunol Immunopathol. 2008;121(3‐4):359 ‐363. PMID:18022248 |
Note on publication | The article describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
