Key features and details | |
Cat. No. | MABL-1895 |
Name | Anti-Human A-type (A1; A2) erythrocytes mAbs |
Clone No. | AFD- W6/1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP |
Species Reactivity | Human |
Basic Information | |
Specificity | W6/1 binds to A1 and A2 erythrocytes and does not bind to B or O erythrocytes (detects a polymorphic determinant of erythrocytes correlating with blood group A). When saturating amounts of secondary antibody are used, binding of W6/1 is 5 times as great on type A1 than A2. |
Alternative Name | |
UniProt | |
Immunogen | W6/1 was prepared by immunizing BALB/c mice with membrane from human tonsil cells (present as a result of contaminating erythrocyte membrane in the tonsil leucocyte preparation). |
Application Notes | W6/1 antibody can be used as an erythrocyte cell type marker and can cause hemogglutination of A-type erythrocytes. |
Antibody First Published | Barnstable et al Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14:9-20 1978 PMID:667938 |
Note on publication | Describes the production of W6/1 antibody and determination of its binding specificity. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
