Key features and details | |
Cat. No. | MABL-1876 |
Name | Anti-hnRNP A2/B1 mAbs |
Clone No. | AFD- GLC82C238 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNPA2/B1 is expressed during proliferation and metastasis of various cancer types and promotes such processes. |
Alternative Name | Heterogeneous nuclear ribonucleoproteins A2/B1; HNRNPA2B1; RNPA2; HNRPA2; HNRPB1; SNRPB1; HNRNPA2; HNRNPB1; IBMPFD2; HNRPA2B1 |
UniProt | P22626 |
Immunogen | The original antibody was generated by immunizing BALB/ mice in the abdominal cavity with human lung cancer cell line GLC82. |
Application Notes | This antibody was used in the immunohistochemical analysis of hnRNP A2/B1 expressed in lung squamous cell carcinoma, alveolar cancer and lung adenocarcinoma tissues. The binding of this antibody to HnRNP A2/B1 antigen was confirmed using western blotting (CN1273489). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
