Anti-HLA Class 1 mAbs

Cat. No.

MABL-1845

Name

Anti-HLA Class 1 mAbs

Clone No.

AFD- W6/32

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, ELISA, FC, IF, IHC

Species Reactivity

Human

Basic Information

Specificity

Recognizes an antigenic determinant shared among products of the HLA A, B and C loci.

Alternative Name

HLA A;B,C; HLA ABC

UniProt

O15506

Immunogen

Human tonsil lymphocyte membranes.

Application Notes

This antibody binds to human human major   histocompatibility complex class I, which is associated with beta   2-microglobulin and expressed on all human nucleated cells. It is a presents  MHC class I antigens and is a central component of of cell-mediated immune   response and tumor surveillance.

Antibody First   Published

Barnstable CJ, Bodmer WF, Brown G, Galfre G, Milstein C, Williams AF, Ziegler A. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for   genetic analysis. Cell. 1978 May;14(1):9-20. PMID:667938

Note on publication

Describes generation of panel of antibodies   including this clone, W6/32.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.