Anti-Glomerular antigen mAbs

Cat. No.

MABL-1703

Name

Anti-Glomerular antigen mAbs

Clone No.

AFD- C5-12

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA

Species Reactivity

Mouse

Basic Information

Specificity

This antibody displays polyreactive binding   to GA, ssDNA, dsDNA and IgG. It does not bind histones or Sm proteins.

Alternative Name

GA

UniProt

Immunogen

This antibody was generated from renal   mononuclear, Ab-producing cells (AbPCs) derived from diseased MRL/pr mouse kidneys. MRL/pr mice spontanously develop an automimmune syndrome associated   with autoantibody production, and act as models of human systemic lupus   erythematosus (SLE).

Application Notes

The binding specificity of this antibody has   been confirmed in ELISA and Western blot analysis (Sekine et al, 2004).

Antibody First   Published

Sekine et al. Enrichment of anti-glomerular antigen antibody-producing cells in the kidneys of MRL/MpJ-Fas(lpr) mice. J   Immunol. 2004 Mar 15;172(6)：3913-21. PMID：15004199

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.