Key features and details | |
Cat. No. | MABL-1701 |
Name | Anti-GITRL mAbs |
Clone No. | AFD- YGL386 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds murine GITRL. |
Alternative Name | TNFSF18L; CD357L;AITRL; TL6; TNLG2A; tumor necrosis factor superfamily member 18; TNF superfamily member 18Glucocorticoid-induced tumour necrosis factor receptor Ligand |
UniProt | |
Immunogen | Recombinant protein injected into DA rats. |
Application Notes | This antibody binds to GITRL and was used in the identification of GITRL and confirmation of its function as the ligand for GITR. |
Antibody First Published | Tone et al. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25): 15059–15064. PMID:14608036 |
Note on publication | Describes the generation of this antibody, characterization of the mGITR/GITRL signalling axis. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |