Key features and details | |
Cat. No. | MABL-1636 |
Name | Anti-Fya mAbs |
Clone No. | AFD- Hima-19 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for the Fya Duffy blood group antigen. |
Alternative Name | Duffy antigen; Human immunochemistry monoclonal antibody-19; Fy(a); Duffy antigen Fya; FY; hima19; hima 19 |
UniProt | Q5Y7A2 |
Immunogen | This human-murine chimeric antibody was derived from the anti-Fya murine monoclonal antibody MIMA-19 (Ab01349); cDNA encoding the VH and VL gene segments from MIMA-19-secreting hybridoma cells were inserted into human IgM expression vectors. |
Application Notes | This antibody has been used to successfully determine the phenotype of DAT-positive red blood cell samples, which are otherwise challenging to phenotype due to the presence of surface-bound autoantibodies and/or complement (Lee et al, 2004). |
Antibody First Published | Lee et al. Applications of murine and humanized chimeric monoclonal antibodies for red cell phenotyping. Br J Haematol. 2004 Jul;126(2):277-81. PMID:15238151 |
Note on publication | Describes the original generation of this antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |