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Anti-Fya mAbs

简要描述:

This antibody is specific for the Fya Duffy blood group antigen.

产品参数:

Cat. No.:MABL-1636

Species:Engineer

Species Reactivity:Human

Type:Recombinate

详细介绍

Key features and   details


Cat. No.

MABL-1636

Name

Anti-Fya mAbs

Clone No.

AFD- Hima-19

From

Recombinant Antibody

Isotype

Engineer antibody

Application


Species Reactivity

Human

Basic Information


Specificity

This antibody is specific for the Fya Duffy blood group antigen.

Alternative Name

Duffy antigen; Human immunochemistry monoclonal   antibody-19; Fy(a); Duffy antigen Fya; FY; hima19; hima 19

UniProt

Q5Y7A2

Immunogen

This human-murine chimeric antibody was derived   from the anti-Fya murine monoclonal antibody MIMA-19 (Ab01349); cDNA encoding   the VH and VL gene segments from MIMA-19-secreting hybridoma cells were   inserted into human IgM expression vectors.

Application Notes

This antibody has been used to successfully determine the phenotype of DAT-positive red blood cell samples, which are otherwise challenging to phenotype due to the presence of surface-bound autoantibodies and/or complement (Lee et al, 2004).

Antibody First   Published

Lee et al. Applications of murine and   humanized chimeric monoclonal antibodies for red cell phenotyping. Br J   Haematol. 2004 Jul;126(2)277-81. PMID15238151

Note on publication

Describes the original generation of this   antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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