Key features and details | |
Cat. No. | MABL-1346 |
Name | Anti-Cytokeratin 8 mAbs |
Clone No. | AFD- 14C2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human cytokeratin 8. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Together with KRT19, cytokeratin 8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
Alternative Name | CK8; CK-8; CK 8; KRT8; CYK8; Keratin type II cytoskeletal 8; Cytokeratin- 8; Type-II keratin Kb8; CGMCC NO 20769; TS1 |
UniProt | P05787 |
Immunogen | The original antibody was generated by immunizing ICR mice with a recombinant polypeptide comprising human cytokeratin 8 cross linked to bovine serum albumin and KLH carrier protein. |
Application Notes | This antibody can recognize human cytokeratin 8 in an ELISA. The affinity constant for the original IgG3 antibody was calculated to be 9.6 × 10^(8) M^(-1). This antibody was used in the immunohistochemical analysis of breast cancer, liver bile duct epithelial cells and adenocarcinoma tissues (CN112940118). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
