Key features and details | |
Cat. No. | MABL-1212 |
Name | Anti-Citreoviridin mAbs |
Clone No. | AFD- 5A10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | food diagnostic, ELISA |
Species Reactivity | Penicillum citreoviridin |
Basic Information | |
Specificity | This antibody binds citreoviridin, which is one of the mycotoxins that contaminates a wide range of agricultural products, including rice, cereal grains and farm crop products. It is produced by Aspergillus terreus, Eupenicillium ochrosalmoneum and Penicillium citreonigrum. It causes cytotoxicity as an uncompetitive inhibitor of ATP hydrolysis. Consuming food which is contaminated with citreoviridin can cause the disease cardiac beri beri. |
Alternative Name | CIT; CTV; Penicillin citreoviridin |
UniProt | |
Immunogen | The original antibody was generated by immunizing BALB/c mice with citreoviridin cross- linked with carrier proteins like BSA and KLH. |
Application Notes | The binding reactivity of this antibody for citreoviridin was determined using ELISA. This antibody can be used for detection of citreoviridin in contaminated food samples. Indirect competitive ELISA (ic-ELISA) indicated that the linear range to detect CIT for this antibody was 25-562 ng/mL with IC50 at 120 ng/mL. The limit of detection was 14.7 ng/mL, and the recovery average was (90.612 ± 3.889)% (PMID: 27622814) |
Antibody First Published | Wang et al. Screening and Molecular Evolution of a Single Chain Variable Fragment Antibody (scFv) against Citreoviridin Toxin. J Agric Food Chem. 2016 Oct 12;64(40):7640-7648. PMID:27622814 |
Note on publication | Describes the generation and characterization of this antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |