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Anti-Citreoviridin mAbs

简要描述:

This antibody binds citreoviridin, which is one of the mycotoxins that contaminates a wide range of agricultural products, including rice, cereal grains and farm crop products. It is produced by Aspergillus terreus, Eupenicillium ochrosalmoneum and Penicillium citreonigrum. It causes cytotoxicity as an uncompetitive inhibitor of ATP hydrolysis. Consuming food which is contaminated with citreoviridin can cause the disease cardiac beri beri.

产品参数:

Cat. No.:MABL-1212

Species:Engineer

Species Reactivity:​Penicillum citreoviridin

Type:Recombinate

Application:food diagnostic, ELISA

详细介绍

Key features and details


Cat. No.

MABL-1212

Name

Anti-Citreoviridin mAbs

Clone No.

AFD- 5A10

From

Recombinant Antibody

Isotype

Engineer antibody

Application

food diagnostic, ELISA

Species Reactivity

Penicillum citreoviridin

Basic Information


Specificity

This antibody binds citreoviridin, which is one   of the mycotoxins that contaminates a wide range of agricultural products, including rice, cereal grains and farm crop products. It is produced by   Aspergillus terreus, Eupenicillium ochrosalmoneum and Penicillium   citreonigrum. It causes cytotoxicity as an uncompetitive inhibitor of ATP   hydrolysis. Consuming food which is contaminated with citreoviridin can cause   the disease cardiac beri beri.

Alternative Name

CIT; CTV; Penicillin citreoviridin

UniProt


Immunogen

The original antibody was generated by   immunizing BALB/c mice with citreoviridin cross- linked with carrier proteins   like BSA and KLH.

Application Notes

The binding reactivity of this antibody for   citreoviridin was determined using ELISA. This antibody can be used for   detection of citreoviridin in contaminated food samples. Indirect competitive   ELISA (ic-ELISA) indicated that the linear range to detect CIT for this   antibody was 25-562 ng/mL with IC50 at 120 ng/mL. The limit of detection was   14.7 ng/mL, and the recovery average was (90.612 ± 3.889)% (PMID: 27622814)

Antibody First Published

Wang et al. Screening and Molecular   Evolution of a Single Chain Variable Fragment Antibody (scFv) against   Citreoviridin Toxin. J Agric Food Chem. 2016 Oct 12;64(40):7640-7648.   PMID:27622814

Note on publication

Describes the generation and   characterization of this antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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