Key features and details | |
Cat. No. | MABL-1086 |
Name | Anti-CD70 mAbs |
Clone No. | AFD- TAN 1-7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block, ELISA, FC, IF |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds to mouse CD70. |
Alternative Name | TNFRS7; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A; TAN1-7; TAN17 |
UniProt | Q05A52 |
Immunogen | Recombinant mouse CD70 (extracellular domain, aa residues 41-195). |
Application Notes | This antibody can be used to detect mouse CD70, the ligand for CD27. The original rat IgG1 format has been used in vivo to inhibit CD70-CD27 mediated induction of interferon gamma following injection of glycolipid activators . |
Antibody First Published | Arora et al. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity. 2014 Jan 16;40(1):105-16 PMID:24412610 |
Note on publication | Describes the generation and initial characterisation of this antibody and its use in vivo. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
