Key features and details | |
Cat. No. | MABL-986 |
Name | Anti-CD45R mAbs |
Clone No. | AFD- YKIX 753.22.2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Depletion, IP, FC |
Species Reactivity | Dog |
Basic Information | |
Specificity | YKIX 753.22 binds specifically to CD45R. CD45R is an isoform of CD45 derived from alternative splicing from a single gene, and is expressed on B cells and peripheral T cells. When used in conjunction with YKIX 716.13, this antibody has been reported to promote cell depletion via antibody-dependent cell- mediated cytotoxicity. |
Alternative Name | CPTPRC; D45 R; L-CA; Leukocyte common antigen; T200; B220; GP180; LCA; LY5; Ly-5; protein tyrosine phosphatase; receptor type C |
UniProt | |
Immunogen | YKIX 753.22.2 was prepared by immunizing DA rats with canine thymocytes. |
Application Notes | YKIX 753.22.2 can be used for FC and IP. It can also be used in conjunction with YKIX 716.13 to promote cell depletion via antibody-dependent cell-mediated cytotoxicity. |
Antibody First Published | Cobbold et al. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994 Mar;43(3):137-54. PMID:8091414 |
Note on publication | Describes the binding specificity and characterisation (by IF staining and FACS, and IP) of antibodies against canine equivalents of human CD antigens. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
