Cat. No.
MABL-2397
Application
neutralize, ELISA
Isotype
Engineer antibody
Species Reactivity
Cowpox virus (CPXV), Monkeypox virus (Mpox), Vaccinia virus (VACV), Variolavirus (VARV)
Clone No.
D21
From
Recombinant Antibody
Specificity
This antibody binds the B6R protein of the monkeypox virus. This antibody also cross reacts with B6R protein of vaccinia virus, variola virus and cowpox virus. Mpox is an infectious disease caused by the monkeypox virus which can be transmitted to humans through physical contact with someone who is infectious, with contaminated materials, or with infected animals. It can cause a painful rash or mucosal lesions which can last 2–4 weeks, enlarged lymph nodes and fever. Monkeypox mortality rates range from 0%-11% in the general population and are higher in young children. In Q3 of 2024, the WHO declared monkeypox a Public Health Emergency of International Concern. This product serves as a powerful tool for related research efforts.
Alternative Names
Mpox; MPXV; Monkeypox virus; Monkey pox virus; MONPV; B6R; MPXVgp167; EEV membrane glycoprotein
UniProt
V9NQJ0
Immunogen
The original antibody was generated from human PBMCs by isolating specific human memory B cells capable of binding Mpox B6R protein.
Application Notes
This antibody is capable of recognizing B6R protein of monkeypox virus, vaccinia virus, variola virus and cowpox virus in an ELISA. In vitro, this antibody was capable of neutralizing VACV infection (CN117466994).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
