Key features and details | |
Cat. No. | MABL-876 |
Name | Anti-CD30 mAbs |
Clone No. | AFD- YMSM636 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Activating, ELISA, FC |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody recognises CD30 which is a receptor for TNFSF8/CD30L. It is thought to regulate cellular growth and lymphocytes development as well as gene expression via NF-kappa-B. |
Alternative Name | TNFRSF8; YMSM 636.4.10; YMSM636; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Lymphocyte activation antigen CD30; Tnfrsf8 |
UniProt | Q60846 |
Immunogen | This antibody was raised by immunising rats with a mouse CD30 - human IgG1 fusion protein. |
Application Notes | This antibody can be used to initiate apoptosis in isolated human peripheral blood eosinophils and thus it might be researched as a potential agent for therapeutic agents for hypereosinophilic diseases useful in the treatment of allergic diseases, respiratory diseases, skin diseases, autoimmune diseases, immunodeficiency diseases, digestive diseases, neoplastic diseases and parasitic infections (US20040156847A1). |
Antibody First Published | Miura et al. Remedies for eosinophilic diseases US20040156847A1 |
Note on publication | This patent describes the application of this antibody in the apoptosis initation in eosinophiles. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
