Cat. No.
MABL-1185
Application
WB, ELISA, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
C2-77
From
Recombinant Antibody
Specificity
This antibody is specific for proto-oncogene c-Fos. cFos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites.
Alternative Names
Proto-oncogene c-Fos; FOS; Cellular oncogene fos; G0/G1 switch regulatory protein 7
UniProt
P01100
Immunogen
This antibody was generated against the proto-oncogene c-Fos.
Application Notes
This antibody is recommended for detection and analysis of cFos by ELISA, immunofluorescence, immunohistochemistry and western blot.
Antibody First Published
Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360
Note on publication
Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
