Cat. No.
MABL-1130
Application
ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
2F11
From
Recombinant Antibody
Specificity
This antibody binds B7-1 (CD80).
Alternative Names
B7.1; CD28L; CD28LG; B7-1; B7; BB1; B7/BB1;T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1; CTLA4L; CTLA-4L
UniProt
P33681
Immunogen
The original antibody was isolated by panning a Fab type Rz human antibody library against CD80 antigen.
Application Notes
This antibody can be used for detection of human B7-1 expressed on Raji B cells by flow cytometry. This antibody can be used for the detection of CD86 in an ELISA. This antibody showed inhibitory effect on T cell activity when used alone or in combination with anti-CD86 antibody 3A2 in an in vitro cell base assay. The use of combination of 3A2 and 2F11 resulted in better inhibition of T cell activity (WO2017105091).
Antibody First Published
WO2017105091
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
