Cat. No.
MABL-797
Application
FC
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
OX-110
From
Recombinant Antibody
Specificity
OX-110 binds specifically to CD200R proteins. CD200R is a type I membrane protein and an inhibitory receptor for the CD200/OX-2 cell surface glycoportein. CD200R acts to limit inflammation by inhibiting expression of pro-inflammatory molecules such as TNF-alpha, interferons and iNOS in response to selected stimuli. CD200R is expressed on rodent myeloid cells and is involved in regulation of macrophage function.
Alternative Names
OX2R; Cell surface glycoprotein CD200 receptor; cell surface glycoprotein CD 200 receptor; CD200 receptor; CD 200 receptor; CD200cell surface glucoprotein receptor; CD 200 cell surface glycoprotein receptor; cell surface glycoprotein OX2 receptor; OX110; MRC OX
UniProt
Q9ES57
Immunogen
OX-110 was generated from rats using immunogenic mouse fusion protein mCD200RCD4d34.
Application Notes
OX-110 can be used to stain in FC.
Antibody First Published
Wright et al. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol 171：3034-46 2003 PMID：12960329
Note on publication
Describes the use of OX-110 in stdying CD200R expression on isolated leukocyte populations.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
