Cat. No.
MABL-322
Application
functional assay, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
12B12C7C3
From
Recombinant Antibody
Specificity
This antibody is specific for TPBG. It does not bind to the same epitope as 39A11G5F2.
Alternative Names
TPBG; M6P1; WAIF1; Trophoblast glycoprotein; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; Wnt-activated inhibitory factor 1
UniProt
Q13641
Immunogen
The original antibody was generated by immunizing BALB/cAnNCrl mice or SJL/JorllcoCrl mice with either full length TPBG or amino acid sequence 32-355 from TPBG.
Application Notes
An ELISA was performed on this antibody with TPBG protein (EP3395834). This antibody was used for flow cytometry on a CHOK1 cell line transformed to contain full-length human TPBG (EP3395834). A cytotoxicity assay was performed on TPBG-negative tumor cell line NCI-H1770 using this antibody conjugated with MMF (EP3395834).
Antibody First Published
Xiaolan et al. Tpbg antibody and preparation method therefor, conjugate and use thereof. EP3395834A4 PMID:
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
