Key features and details | |
Cat. No. | MABL-262 |
Name | Anti-Morphine mAbs |
Clone No. | AFD-MOR158 (MOR158.1.3) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | RIA, ELISA |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody binds morphine and cross reacts with other opioids like codeine, ethylmorphine, dihydromorphine, dihydrocodeine, dihydromorphinone, dihydrocodeinone, norcodeine, naloxone and naltrexone. Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (Papaver somniferum). It is considered the classic opioid analgesic, most commonly used in pain management, morphine provides major relief to patients afflicted with pain. It is a non-synthetic narcotic with a high potential for abuse. |
Alternative Name | Morphium; Codeine; Ethylmorphine; Dihydromorphine; Dihydrocodeine; Dihydromorphinone; Dihydrocodeinone; Norcodeine; Naloxone; Naltrexone; ChEBI: 17303 |
UniProt | |
Immunogen | The original antibody was generated by immunizing female BALB/c mice with morphine-BSA conjugate. |
Application Notes | The initial binding reactivity and cross reactivity of this antibody to morphine and other opiods was determined using ELISA and radioimmunoassay (PMID: 3211162; 8417377). |
Antibody First Published | Sawada et al. Production and characterization of high-affinity monoclonal antibodies against morphine. Mol Immunol. 1988 Sep;25(9):937-43. PMID:3211162 |
Note on publication | Describes the generation and characterization of twelve antibodies against morphine. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |