Key features and details | |
Cat. No. | MABL-225 |
Name | Anti-IQGAP2 mAbs |
Clone No. | AFD-A2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IF |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for human and murine IQGAP2. IQGAP2 binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. |
Alternative Name | Ras GTPase-activating-like protein IQGAP2 |
UniProt | Q13576 |
Immunogen | The original mouse version of this antibody was raised by immunizing A/J mice with his- tagged human IQGAP2. |
Application Notes | Aliquots of chronically infected or uninfected N2a cells were used for immunofluorescence with the mouse version of this antibody. This was done to research genes associated with prion propagation (Marbiah et al, 2014; pmid:24843046). |
Antibody First Published | Marbiah et al. Identification of a gene regulatory network associated with prion replication EMBO J. 2014 Jul 17;33(14):1527-47. PMID:24843046 |
Note on publication | A gene regulatory network associated with prion propagation at the ECM and governed by the cellular differentiation state was indentified. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
