Key features and details | |
Cat. No. | MABL-140 |
Name | Anti-GluA1/GluR1 glutamate receptor mAbs |
Clone No. | AFD-N355/1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IHC |
Species Reactivity | Rat, Mouse |
Basic Information | |
Specificity | This antibody is specific for GluA1/GluN1 glutamate receptor epitope: amino acids 1-389. The antibody does not cross react with GluR2. GluR1 is a ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. |
Alternative Name | N355/1R; Glutamate receptor 1; Gria1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1 |
UniProt | P19490 |
Immunogen | This antibody was raised by immunising BALB/c mice with GluA1/GluN1 glutamate receptor epitope: amino acids 1-389 |
Application Notes | The IgG1 version of this antibody has been used for a western blot on hippocampal proteins of mice and proteins from the brains of rats (Bellizi et al, 2016; PMID:26818520) (Zhang et al, 2018; PMID:30181277). Immunohistochemistry was preformed on the brain of a rat with the IgG1 version of this antibody (Gong et al, 2016; PMID:26644354). |
Antibody First Published | Gong et al Developing high-quality mouse monoclonal antibodies for neuroscience research - approaches, perspectives and opportunities N Biotechnol. 2016 Sep 25;33(5 Pt A):551-64. PMID:26644354 |
Note on publication | Describes the need for good antibodies usable is neurological research and the creation of these antibodies |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
