Key features and details | |
Cat. No. | MABL-086 |
Name | Anti-Slo1/BKAlpha maxi-K+ channel mAbs |
Clone No. | AFD-L6/23 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IHC, IP |
Species Reactivity | Rat, Mouse |
Basic Information | |
Specificity | This antibody is specific for Slo1. |
Alternative Name | L6/23R; Calcium-activated potassium channel subunit alpha-1; Calcium- activated potassium channel; subfamily M subunit alpha-1; KCa1.1, K(VCA)alpha; BK channel; BKCA alpha; Maxi K channel; Slo-alpha; Slowpoke homolog; Kcnma1; Kcnma, |
UniProt | Q08460 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein corresponding to the cytoplasmic C-terminus (amino acids 690-1196) of mouse Slo1. |
Application Notes | The specificity of this antibody has been confirmed in western blot analysis of rat and mouse brain membrane preparations, with no bands detected in blots of brain membrane preparations from BKAlpha knockout mice (Wersinger et al, 2010). This antibody has been used in immunoblot analysis of membranes prepared from adult rat and mouse brain (Andrews et al, 2019; PMID:30667360). |
Antibody First Published | Wersinger et al. BK Channels Mediate Cholinergic Inhibition of High Frequency Cochlear Hair Cells PLoS One. 2010;5(11):e13836. PMID:21079807 |
Note on publication | Describes the original characterisation of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
