Key features and details | |
Cat. No. | MABL-084 |
Name | Anti-SynDIG1 mAbs |
Clone No. | AFD-L42/17 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IB, IP |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for SynDIG1. |
Alternative Name | L42/17R; Synapse differentiation-inducing gene protein 1; Dispanin subfamily C member 2; Transmembrane protein 90B; DSPC2; Tmem90b; C20orf39 |
UniProt | A2ANU3 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein corresponding to the cytoplasmic N-terminus (amino acids 1-183) of mouse SynDIG. |
Application Notes | The specificity of this antibody has been confirmed in immunoblot analysis of extracts from HEK293 and COS cells transfected with HA-SynDIG1, where this antibody recognises a single band (Kalashnikova et al, 2010), This antibody has been used in immunoblot analysis of membranes prepared from adult rat (Andrews et al, 2019; PMID:30667360) and mouse brain (Kalashnikova et al, 2010).Additionally, this antibody has been used to immunoprecipitate P14 mouse brain extracts (Kalashnikova et al, 2010). |
Antibody First Published | Kalashnikova et al. SynDIG1: An Activity-Regulated, AMPA- Receptor- Interacting Transmembrane Protein that Regulates Excitatory Synapse Development Neuron. 2010 Jan 14;65(1):80-93. PMID:20152115 |
Note on publication | Describes the original generation of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
