Cat. No.
MABL-3705
Application
Block
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
ABT-874 (Briakinumab)
From
Recombinant Antibody
Specificity
Binds to human IL12 and IL23 via IL-12/23p40.
Alternative Names
IL-12p40; Interleukin 12; Interleukin 23; IL12; IL23; IL-12; IL-23
UniProt
P29460
Immunogen
This antibody was generated by phage display technology.
Application Notes
This antibody binds to and neutralises human IL12 and IL23.
Antibody First Published
Sandborn How future tumor necrosis factor antagonists and other compounds will meet the remaining challenges in Crohn's disease. Rev Gastroenterol Disord. 2004;4 Suppl 3:S25-33. PMID:15583528
Note on publication
Discusses the potential of this antibody in the treatment of Crohn's disease.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
