Cat. No.
MABL-3694
Application
Activate, IP, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
EP3-1
From
Recombinant Antibody
Specificity
Shown to bind to epitopes of sequences; LLHGDFHAFSAG-GGGC-NH2, LLHGDFH-GGGC-HN2, and FHAFSAG-GGGC-NH2, but showed no reactivity to live HeLa cells by IF.
Alternative Names
LAT1; E16; MPE16; SLC7A5
UniProt
Q01650
Immunogen
Immunised mice and constructed IgG1 Fab phage display libraries from the spleen cells. CD98-reactive recombinant Fab fragments were retrieved by epitope peptide panning.
Application Notes
CD98 may be a target for T or B cell immune responses against tumour cells in cancer patients (Itoh 2008).
Antibody First Published
Itoh Antibody epitope peptides as potential inducers of IgG antibodies against CD98 oncoprotein. Cancer Sci. 2009 Jan;100(1):126-31. PMID:19018757
Note on publication
Describes generation of antibody and potential for therapeutic use in initiating immune response against cancer.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
