Cat. No.
MABL-3665
Application
CoStim, IP, WB, Block, FC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
7G6
From
Recombinant Antibody
Specificity
Recognises an epitope shared by 145-150kDa and 190kDa complement receptor proteins, originally designated CR2 (CD21) and CR1 (CD35).
Alternative Names
CD21 & CD35
UniProt
P19070 & P17927
Immunogen
Purified Mouse CR1.
Application Notes
This antibody binds mouse complement receptors CR1 and CR2, functionally blocking CR2 leading to suppression of a normal antibody immune response (see Heyman et al. 1990, PMID: 1695671)
Antibody First Published
Kinoshita et al. Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative. J Immunol. 1988 May 1;140(9):3066-72 PMID:2966205
Note on publication
Describes the generation and characterization of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
