Key features and details | |
Cat. No. | MABL-3328 |
Name | Anti-Bla g 2 mAbs |
Clone No. | AFD-7C11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | crystallography, ELISA |
Species Reactivity | German Cockroach (B. germanica) |
Basic Information | |
Specificity | This antibody binds to the N-terminal lobe of Bla g 2. |
Alternative Name | Cockroach Allergen; Aspartic protease Bla g 2; Blattella germanica allergen |
UniProt | P54958 |
Immunogen | Bla g 2, a major cockroach allergen. |
Application Notes | This antibody binds to Bla g 2 via an epitope commonly used by allergogenic IgE, however distinct from the epitope used by anti-Bla g 2 antibody clone 4C3 also available through Absolute Antibody. Both antibodies may be used in a sandwich ELISA. F(ab')2 versions of this antibody have been used in co-crystallization studies of Bla g 2. |
Antibody First Published | Li et al. Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem. 2008 Aug 15;283(33):22806-14. PMID:18519566 |
Note on publication | Describes isolation of B-cells from patients, preparation of cDNA libraries as well as generation and characterization of anti-Phl p 5 scFv 4.2 . |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
