Key features and details | |
Cat. No. | MABL-3584 |
Name | Anti-SARS-CoV S glycoprotein mabs |
Clone No. | F26G19 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | NTRL, WB, ELISA, IF |
Species Reactivity | SARSCoronavirus |
Basic Information | |
Specificity | This antibody specifically binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein. The originally characterized human IgG1 had a binding affinity of KD=4.05 (±1.01) nM. |
Alternative Name | Spike protein; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S1 |
UniProt | P59594 |
Immunogen | The original antibody was generated by immunizing the BALB/C mice with the Tor-3 strain of the SARS-CoV. |
Application Notes | This antibody is a SARS-CoV neutralizing antibody. Applications include ELISA, Western blotting, Immunofluorescence (Berry et al, 2004). |
Antibody First Published | Berry et al. Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus Journal of Virological Methods (2004); Issue:1; Volume: 120; Pages: 87-96. PMID:15234813 |
Note on publication | Describes the development and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
