Key features and details | |
Cat. No. | MABL-2365 |
Name | Anti-MHC class II mAbs |
Clone No. | AFD- DC8 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FACS |
Species Reactivity | Mouse |
Basic Information | |
Specificity | The antibody is specific for MHC class II. |
Alternative Name | VHHDC8; H2-Ab1; H2-iabeta; H-2 class II histocompatibility antigen A beta chain; MHC class II antigen A beta; MHC-II A beta |
UniProt | P14483 |
Immunogen | |
Application Notes | The original format of the antibody stained splenocytes by FACS analysis. 18F labeled antibody was successfully used to detect lymphoid organs and reveal tumors in mice (Rashidian et al., 2015; PMID: 26630549). Texas Red-conjugated antibody was employed for staining of lymphoid organs (Rashidian et al., 2015; PMID: 26955657). |
Antibody First Published | Rashidian et al. Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics Angew Chem Int Ed Engl. 2016 Jan 11;55(2):528-533. doi: 10.1002/anie.201507596. Epub 2015 Dec 2. PMID:26630549 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |