Key features and details | |
Cat. No. | MABL-1352 |
Name | Anti-D-Dimer mAbs |
Clone No. | AFD- 3A8 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds fragment D chains of fibrinogen (Fragment D), also called D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder. |
Alternative Name | XDP; Fragment D-dimer; Fibrin degradation fragment; Fibrin degradation product; Fibrin |
UniProt | P02671 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with human D-dimer as an immunogen. |
Application Notes | The initial binding characterization of this antibody to human D-dimer fragment was done using ELISA. DD-3A8 and DD-2E7 bind different epitope of the human D-dimer fragment and can be used as antibody pair for detection of blood coagulation, where DD-3A8 acts as a capture antibody and DD- 2E7 is used as detection antibody. The sensitivity of the double sandwich ELISA was reported to be 0.25 μg/ml (CN111057149). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |