Key features and details | |
Cat. No. | MABL-1138 |
Name | Anti-CD83 mAbs |
Clone No. | AFD- HB15e |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human CD83. |
Alternative Name | hCD83; B-cell activation protein; Cell surface protein HB15 |
UniProt | Q01151 |
Immunogen | This original antibody was raised by immunizing a mouse with human CD83. |
Application Notes | The original antibody was used for an ELISA on huCD83Ig fusion protein. Here it showed that the binding of this antibody to CD83 is inhibited by ELBE-1. This antibody was used for flow cytometry on huCD83-expressing cells (Papp et al., 2013; PMID：23607344), and on activated human dendritic cells (Cao et al., 2005; PMID：15320871, Pashine et al., 2008; PMID：18079004). This antibody was used for a western blot on HuCD83Ig fusion protein (Papp et al., 2013; PMID：23607344), and on human CD83 fusion proteins (Pashine et al., 2008; PMID：18079004). |
Antibody First Published | Skrnjug et al. The Mucosal Adjuvant Cyclic di-AMP Exerts Immune Stimulatory Effects on Dendritic Cells and Macrophages PLoS One. 2014; 9(4)：24755640 |
Note on publication | The original antibody reports on the identification of dendritic cells and macrophages as target cells of c-di-AMP. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
